Endocrine Abstracts

A 26-year-old Caucasian female presented with nausea, intermittent abdominal pain and amenorrhoea of 3 months duration. She was known to have Von Hippel–Lindau disease (Exon 3A/T 742 mutation) and had undergone surgery for cerebellar haemangioblastoma. She also had presumed dermoid cyst in right ovary which had been monitored by ultrasound. Ultrasound revealed an increase in size and vascularity of right ovarian cyst. MRI scan revealed it to be a 6.3 cm lobulated mass in ...

We describe a case of 38 year old female of Indian origin who presented with symptoms of Graves disease to our clinic. She had a diffusely enlarged goitre and minimal eye signs. Her T4 was 62 pmol/L(9–24), T3 9 pmol/L(3.5–6.5), and TSH was <0.01 mu/L (0.3–5.0). Radioactive iodine uptake scan revealed the presence of increased uptake throughout the gland. She was treated with carbimazole for 18 months and is in remission at present.Abou...

We describe a case of parathyroid carcinoma which is a rare, yet important cause of primary hyperparathyroidism.A 22 year old soldier was referred by army medical officer because of abnormal blood test results. He gave a history of weight loss of about 10 kg, increasing shortness of breath and malaise for 1 month prior to presentation. His past medical history was unremarkable, he was a non smoker and did not drink alcohol. He was not on any regular trea...

We describe our patient, a 50 year old lady who developed Addisons disease 10 years ago with typical signs and symptoms of weight loss, hyperpigmentation, tiredness and postural hypotension. She is under follow up at our clinic for last 4 years. Her identical twin was diagnosed with Addisons disease and hypothyroidism at age 27 and with Coeliac disease when she was 43. Both of them are positive for anti-adrenal and TPO antibodies.Our patient developed le...

A 34-year-old male presented in March 2006 to the eye department with reduced visual acuity in left eye over 2 months and was initially diagnosed as retrobulbar neuritis. His vision was not improving in the next 2 months and so an MRI of the optic nerve was arranged which revealed a pituitary tumour impinging on the optic chiasma and his visual fields showed an early bitemporal hemianopia. Initial bloods revealed T4 13.5 pmol/l, TSH 1.4 μ/l, cortisol 305 nmol/l, prolactin...